Durlobactam (sodium)

• UNSPSC Description:

  Durlobactam sodium salt (ETX2514) is a broad-spectrum β-lactamase inhibitor with IC50s of 4, 14 and 190 nM for Class A KPC-2, Class C AmpC and Class D OXA-24, respectively. For the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/Durlobactam_sodium_salt.html

• Purity:

  99.62

• Solubility:

  H2O : ≥ 100 mg/mL

• Smiles:

  NC([C@H]1[N@@]2C(N([C@H](C=C1C)C2)OS(=O)(O[Na])=O)=O)=O

• Molecular Weight:

  299.24

• References & Citations:

  [1]Durand-Réville TF, et al. ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Nat Microbiol. 2017 Jun 30;2:17104.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  1467157-21-6