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Monomethyl kolavate

CAT: 0013-GTR19181016Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19181016Size:5 mg
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Description
Monomethyl kolavate is a potent and selective inhibitor of Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH), exhibiting an IC50 of 12 μM. This small molecule is a valuable chemical tool for studying trypanosome metabolism in vitro and for probing TbGAPDH as a potential drug target against African sleeping sickness.
CAS Number
24513-41-5
Field of Research
Infectious Disease & Virology
Smiles
COC (=O) \C=C (/C) CC[C@@]1 (C) [C@H] (C) CC[C@]2 (C) [C@@H]1CCC=C2C (O) =O
Molecular Formula
C21H32O4
Molecular Weight
348.48
Storage Conditions
-20°C
Notes
For research use only.