TPB15

CAT: 0013-GTR19185812-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19185812-01Size:25 mg

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Description

TPB15 is an orally bioavailable small molecule inhibitor of Hedgehog signaling that acts by blocking Smoothened ciliary translocation and reducing its expression. It demonstrates potent anti-proliferative and pro-apoptotic activity in vitro, such as in MDA-MB-468 cells, and shows promising in vivo anti-tumor efficacy with a favorable toxicity profile.

CAS Number

2170347-69-8

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Smiles

ClC=1C (C=2N3C (=NN2) C (Cl) =CC=C3) =CC (NC (=O) C4=C (Cl) N=C (Cl) C=C4) =CC1

Molecular Formula

C18H9Cl4N5O

Molecular Weight

453.11

Storage Conditions

-20°C

Notes

For research use only.

Alternative Products

Catalog	Name
HY-147670	TPB15

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