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C-Fms-IN-12

CAT: 0013-GTR19184554-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19184554-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C-Fms-IN-12 is a small molecule inhibitor targeting FMS and c-KIT kinases, shown to induce apoptosis in A549 lung cancer cells in vitro. Its broad-spectrum anti-cancer potential is supported by research demonstrating therapeutic effects across various cancer models in preclinical studies.
CAS Number
2145102-33-4
Field of Research
Cell Biology, Signal Transduction
Smiles
O (C=1C (NC (NC2=CC (OC) =CC (OC) =C2) =O) =CN=C (NC3=CC=C (C=C3) N4CCOCC4) N1) C5=CC (OC) =CC=C5
Molecular Formula
C30H32N6O6
Molecular Weight
572.61
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-(3,5-Dimethoxyphenyl)-3-[4-(3-methoxyphenoxy)-2-(4-morpholin-4-ylanilino)pyrimidin-5-yl]urea
CAS Number2145102-33-4
PubChem CID142749657
IUPAC Name1-(3,5-dimethoxyphenyl)-3-[4-(3-methoxyphenoxy)-2-(4-morpholin-4-ylanilino)pyrimidin-5-yl]urea
Molecular FormulaC30H32N6O6
Molecular Weight572.6
XLogP4.2
Topological Polar Surface Area128
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count10
Heavy Atom Count42
Formal Charge0
Complexity801
SMILES
COC1=CC(=CC=C1)OC2=NC(=NC=C2NC(=O)NC3=CC(=CC(=C3)OC)OC)NC4=CC=C(C=C4)N5CCOCC5
InChI
InChI=1S/C30H32N6O6/c1-38-23-5-4-6-24(17-23)42-28-27(34-30(37)33-21-15-25(39-2)18-26(16-21)40-3)19-31-29(35-28)32-20-7-9-22(10-8-20)36-11-13-41-14-12-36/h4-10,15-19H,11-14H2,1-3H3,(H,31,32,35)(H2,33,34,37)
InChIKey
SBLCNWNDMUJOKH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(3,5-Dimethoxyphenyl)-3-[4-(3-methoxyphenoxy)-2-(4-morpholin-4-ylanilino)pyrimidin-5-yl]urea
CAS: 2145102-33-4
CID: 142749657
Formula: C30H32N6O6
MW: 572.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight572.6
XLogP34.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count10
Exact Mass572.23833276
Monoisotopic Mass572.23833276
Topological Polar Surface Area128 Ų
Heavy Atom Count42
Formal Charge0
Complexity801
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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