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MCPA-13C8

CAT: 804-HY-B0859SSize: 1 mgDry Ice: NoHazardous: No
1 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MCPA-13C8 is the 13C-labeled MCPA (HY-B0859) . MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds[1][2][3][4][5][6].
Product Name Alternative
4-Chloro-2-Methylphenoxyacetic acid-13C8
UNSPSC
12352005
Target
Cytochrome P450; Herbicide; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mcpa-13c8.html
Solubility
10 mM in DMSO
Smiles
O=[13C](O)[13CH2]O[13C]1=[13CH][13CH]=[13C](Cl)[13CH]=[13C]1C
Molecular Formula
C 13C8H9ClO3
Molecular Weight
208.56
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Kimura O, et al. Uptake of 4-chloro-2-methylphenoxyacetic acid (MCPA) from the apical membrane of Caco-2 cells by the monocarboxylic acid transporter. Toxicol Appl Pharmacol. 2008 Mar 15;227 (3) :325-30.|[3]Peixoto F P, et al. Toxicity of MCPA on non-green potato tuber calli. Acta Physiologiae Plantarum, 2009, 31 (1) : 103-109.|[4]Gao Y F, et al. The influence of chlorophenoxy herbicides MCPA on creeping bentgrass physiological index. Advanced Materials Research, 2012, 356: 2763-2766.|[5]Inomata N, et al. Effects of MCPA and other phenoxyacid compounds on hepatic xenobiotic metabolism in rats. Tohoku J Exp Med. 1991 Nov;165 (3) :171-82.|[6]van Ravenzwaay B, et al. Absorption, distribution, metabolism and excretion of 4-chloro-2-methylphenoxyacetic acid (MCPA) in rats. Food Chem Toxicol. 2004 Jan;42 (1) :115-25.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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