MCPA

• Description:

  MCPA is an orally active phenoxyacetic acid herbicide. MCPA interferes with membrane integrity, energy metabolism (decreases ATP levels), and redox balance in plant cells. MCPA increases hepatic cytochrome P-450 levels and increases aniline hydroxylase and 7-ethoxycoumarin O-deethylase activities. MCPA can be used to control broadleaf weeds[1][2][3][4][5].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H318, H410

• Target:

  Cytochrome P450; Herbicide

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/mcpa.html

• Purity:

  98.95

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(O)COC1=CC=C(Cl)C=C1C

• Molecular Formula:

  C9H9ClO3

• Molecular Weight:

  200.62

• Precautions:

  H302, H315, H318, H410

• References & Citations:

  [1]Kimura O, et al. Uptake of 4-chloro-2-methylphenoxyacetic acid (MCPA) from the apical membrane of Caco-2 cells by the monocarboxylic acid transporter. Toxicol Appl Pharmacol. 2008 Mar 15;227 (3) :325-30.|[2]Peixoto F P, et al. Toxicity of MCPA on non-green potato tuber calli. Acta Physiologiae Plantarum, 2009, 31 (1) : 103-109. |[3]Gao Y F, et al. The influence of chlorophenoxy herbicides MCPA on creeping bentgrass physiological index. Advanced Materials Research, 2012, 356: 2763-2766. |[4]Inomata N, et al. Effects of MCPA and other phenoxyacid compounds on hepatic xenobiotic metabolism in rats. Tohoku J Exp Med. 1991 Nov;165 (3) :171-82.|[5]van Ravenzwaay B, et al. Absorption, distribution, metabolism and excretion of 4-chloro-2-methylphenoxyacetic acid (MCPA) in rats. Food Chem Toxicol. 2004 Jan;42 (1) :115-25.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [94-74-6]