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IRES-J007

CAT: 0013-GTR19178131Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19178131Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IRES-J007 ia an improved IRES inhibitor that blocks IRES-hnRNP A1 binding; binds to a small pocket structure within the RRM-containing fragment of hnRNP A1 (UP1 fragment), inhibits cyclin D1 and c-MYC IRES activity to a greater extent compared with C11 (IRES-C11) ; significantly reduces tumor growth of GBM xenografts in mice, and markedly reduces the mRNA translational state of cyclin D1 and c-MYC transcripts combined with PP242.
CAS Number
155514-72-0
Purity
>98%
Smiles
O (C ([H]) ([H]) [H]) C1C ([H]) =C (C ([H]) =C ([H]) C=1C ([H]) ([H]) N1C (C2=C ([H]) C ([H]) =C ([H]) C ([H]) =C2C1=O) =O) OC ([H]) ([H]) [H]
Molecular Formula
C17H15NO4
Molecular Weight
297.3053
Notes
For research use only.

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Alternative Products

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MBS3602211IRES-J007
sc-235437AJosiphos SL-J007-2
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P45067DmBACCS2-IRES-dOrai-IRES-GFP
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PVT59639dmBACCS2-IRES-dOrai-IRES-GFP Plasmid
BUP21238-01IRES-C11
BZ38048PMLAV-IRES-PITX2 (human) -IRES-EGFP-Puro
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