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Cabozantinib S-malate

CAT: 0013-GTR19178076-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19178076-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cabozantinib S-malate (XL184) is the malate salt of the small molecule kinase inhibitor cabozantinib. This orally available compound is used in cancer research, where it has demonstrated activity in both in vitro assays and in vivo models targeting various receptor tyrosine kinases.
CAS Number
1140909-48-3
Product Name Alternative
XL-184, XL184, XL 184, TAMReceptor, TAM Receptor, VEGFR, VEGFR3/FLT4, VEGFR2/KDR, cMet, cMet/HGFR, c-Met, cKit, Apoptosis, AXL, Cabozantinib, Cabozantinib Malate, Cabozantinib S malate, Cabozantinib Smalate, Cabozantinib S-malate, BMS 907351, BMS907351, BMS-907351, Kit, HGFR
Field of Research
Cardiovascular Research, Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:16.67 mg/mL (26.23 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O[C@@H] (CC (O) =O) C (O) =O.COc1cc2nccc (Oc3ccc (NC (=O) C4 (CC4) C (=O) Nc4ccc (F) cc4) cc3) c2cc1OC
Molecular Formula
C32H30FN3O10
Molecular Weight
635.59
Storage Conditions
-20°C
Notes
For research use only.

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