Momelotinib

CAT: 0013-GTR19177974-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19177974-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

Momelotinib (CYT387) is a potent and orally bioavailable JAK1/2 inhibitor (IC50: 11 nM/18 nM) that blocks ATP binding, disrupting JAK-STAT signaling. This action leads to inhibited proliferation and induced apoptosis in relevant tumor cells, as demonstrated in cellular and animal models of myeloproliferative neoplasms.

CAS Number

1056634-68-4

Product Name Alternative

Momelotinib, JAK3, Janus kinase, JAK1, JAK2, JAK, inhibit, LM 1149, LM1149, LM-1149, Inhibitor, Apoptosis, Autophagy, CYT 11387, CYT 387, CYT387, CYT-387, CYT11387, CYT-11387

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

97.07% (May vary between batches)

Solubility

DMSO:62.5 mg/mL (150.8 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.41 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

O=C (NCC#N) c1ccc (cc1) -c1ccnc (Nc2ccc (cc2) N2CCOCC2) n1

Molecular Formula

C23H22N6O2

Molecular Weight

414.46

Storage Conditions

-20°C

Notes

For research use only.

Alternative Products

Catalog	Name
T1849-01	Momelotinib
GSB63606-01	Momelotinib sulfate
MBS3846085-01	Momelotinib Mesylate
JH920534	Momelotinib Dihydrochloride
C08367-50mg	Momelotinib (CYT387)
HY-10963	Momelotinib (mesylate)
AR-M05041-01	Momelotinib-d4
CS-O-53329	Momelotinib-d8
HY-10962-01	Momelotinib (sulfate)
T70823-01	Momelotinib HCl

Momelotinib

Alternative Products

Popular Products