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CX516

CAT: 0013-GTR19177907-02Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19177907-02Size:1 ml x 10 mM (in DMSO)
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Description
CX516 (Ampalex) is a nootropic ampakine that functions as a positive allosteric modulator of AMPA receptors. It is utilized in research for cognitive disorders such as Alzheimer's disease, schizophrenia, and MCI, with studies conducted in both in vitro and in vivo experimental models.
CAS Number
154235-83-3
Product Name Alternative
Modulator, inhibit, Ionotropic glutamate receptors, iGluR, Inhibitor, CX516, CX-516, CX 516, BDP12, BDP-12, BDP 12, ampakine, Ampakine CX 516, Ampakine CX516, Ampakine CX-516, Ampalex, AMPA, Alzheimer, allosteric, positive, receptor, schizophrenia
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
≥95% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.29 mM) ; DMSO:50 mg/mL (207.22 mM)
Smiles
O=C (N1CCCCC1) C1=CC2=NC=CN=C2C=C1
Molecular Formula
C14H15N3O
Molecular Weight
241.29
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

1-(Quinoxalin-6-ylcarbonyl)piperidine

CX-516 is a N-acylpiperidine.

CAS Number154235-83-3
PubChem CID148184
IUPAC Namepiperidin-1-yl(quinoxalin-6-yl)methanone
Molecular FormulaC14H15N3O
Molecular Weight241.29
XLogP1.8
Topological Polar Surface Area46.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count18
Formal Charge0
Complexity301
SMILES
C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2
InChI
InChI=1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2
InChIKey
ANDGGVOPIJEHOF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(Quinoxalin-6-ylcarbonyl)piperidine
CAS: 154235-83-3
CID: 148184
Formula: C14H15N3O
MW: 241.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight241.29
XLogP31.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass241.121512110
Monoisotopic Mass241.121512110
Topological Polar Surface Area46.1 Ų
Heavy Atom Count18
Formal Charge0
Complexity301
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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