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Erastin

CAT: 0013-GTR19177739-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177739-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Erastin is a ferroptosis-inducing compound that activates mitochondrial VDAC channels in a ROS- and iron-dependent manner. It exhibits selective anti-tumor activity against cells harboring RAS mutations and is widely used in vitro and in vivo to study ferroptosis mechanisms and oncogenic signaling in cancer research.
CAS Number
571203-78-6
Product Name Alternative
Inhibitor, Erastin, Ferroptosis, inhibit, VDAC, Voltage-dependent anion channel
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
97.03% (May vary between batches)
Solubility
DMSO: 25 mg/mL (45.7 mM), Sonication is recommended. Ethanol: < 1 mg/mL (insoluble or slightly soluble) . H2O: < 1 mg/mL (insoluble or slightly soluble) .
Smiles
CCOc1ccccc1-n1c (nc2ccccc2c1=O) C (C) N1CCN (CC1) C (=O) COc1ccc (Cl) cc1
Molecular Formula
C30H31ClN4O4
Molecular Weight
547.04
Storage Conditions
Store at low temperature. Powder: -20°C for 3 years. In solvent: -80°C for 1 year.
Notes
For research use only.

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