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Tazemetostat

CAT: 0013-GTR19177679-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177679-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tazemetostat (EPZ6438) is a potent, selective, and orally bioavailable SAM-competitive inhibitor of the EZH2 histone methyltransferase (IC50=11 nM) . It demonstrates antitumor efficacy in preclinical models and is used in research for cancers like epithelioid sarcoma and follicular lymphoma, supporting both in vitro and in vivo experimental studies.
CAS Number
1403254-99-8
Product Name Alternative
EPZ-6438
Field of Research
Cancer Biology, Epigenetics & Chromatin, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
EZH2 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
CCN (C1CCOCC1) c1cc (cc (C (=O) NCc2c (C) cc (C) [nH]c2=O) c1C) -c1ccc (CN2CCOCC2) cc1
Molecular Formula
C34H44N4O4
Molecular Weight
572.8
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[ (1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl) methyl]-5-[ethyl (tetrahydro-2H-pyran-4-yl) amino]-4-methyl-4'- (4-morpholinylmethyl) -[1,1'-biphenyl]-3-carboxamide

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HY-13803-01Tazemetostat
CS-O-60916Tazemetostat-d5
HY-13803CTazemetostat (hydrobromide)
HY-13803R-01Tazemetostat (Standard)
T15240-01Tazemetostat trihydrochloride
BUP15347-01Tazemetostat hydrobromide
414057Tazemetostat HBr
CS-O-52290Tazemetostat-d8
T70588-01Tazemetostat HCl

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