Tazemetostat

• Target:

  Apoptosis|||Histone Methyltransferase

• Related Pathways:

  Chromatin/Epigenetic|||Apoptosis

• Purity:

  0.9984

• Bioactivity:

  Tazemetostat (EPZ6438) is a histone methyltransferase EZH2 inhibitor (IC50=11 nM) that is orally active, selective, and SAM-competitive. Tazemetostat exhibits antitumor activity and may be used for the treatment of epithelioid sarcoma/follicular lymphoma.

• Smiles:

  CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCOCC2)cc1

• Molecular Formula:

  C34H44N4O4

• Molecular Weight:

  572.74

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1403254-99-8