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Tazemetostat

CAT: 0931-T1788-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T1788-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1403254-99-8
Target
Apoptosis, Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic, Apoptosis
Purity
0.9984
Bioactivity
Tazemetostat (EPZ6438) is a histone methyltransferase EZH2 inhibitor (IC50=11 nM) that is orally active, selective, and SAM-competitive. Tazemetostat exhibits antitumor activity and may be used for the treatment of epithelioid sarcoma/follicular lymphoma.
Smiles
CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCOCC2)cc1
Molecular Formula
C34H44N4O4
Molecular Weight
572.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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