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GNF4877

CAT: 0013-GTR19177304-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177304-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNF4877 is a potent small molecule inhibitor of DYRK1A and GSK3β with IC50 values of 6 nM and 16 nM, respectively. It promotes β-cell proliferation by blocking NFATc nuclear export, making it a valuable research tool for studying diabetes and regenerative biology in both cellular and animal models.
CAS Number
2041073-22-5
Product Name Alternative
DYRK, DYRK1A, Dual specificity tyrosine phosphorylation regulated kinase, Dual specificity tyrosine regulated kinase, GNF 4877, GNF4877, GNF-4877, Glycogen synthase kinase-3, Glycogen synthase kinase 3, GSK-3, GSK3, GSK3β, GSK-3β, Inhibitor, inhibit
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.63% (May vary between batches)
Solubility
DMSO:10 mg/mL (20.22 mM)
Smiles
CC (C) Oc1ccc (F) c (c1) -c1cnc (N) c (n1) C (=O) Nc1cnccc1N1CCC[C@H] (C1) C (O) =O
Molecular Formula
C25H27FN6O4
Molecular Weight
494.52
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T11447-01GNF4877
bs-60294C-01GNF4877 --- β Cell Proliferation Inducer

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