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Eltanexor

CAT: 0013-GTR19177181-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177181-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Eltanexor (ONO-7706) is an orally bioavailable, potent inhibitor of exportin-1 (XPO1) with an EC50 of 60.9 nM. It induces caspase-dependent apoptosis in leukemic cell lines and has demonstrated anti-leukemic activity in preclinical in vitro and in vivo research models.
CAS Number
1642300-52-4
Product Name Alternative
ATG 016, ATG016, ATG-016, Eltanexor, KPT8602, KPT-8602, KPT 8602, ONO7706, ONO-7706, ONO 7706, XPO1
Field of Research
Pharmacology & Drug Discovery
Purity
≥98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.71 mM) ; DMSO:80 mg/mL (186.79 mM) ; H2O:< 0.1 mg/mL (insoluble)
Smiles
NC (=O) C (=C 1cnc (n1) -c1cc (cc (c1) C (F) (F) F) C (F) (F) F) \c1cncnc1
Molecular Formula
C17H10F6N6O
Molecular Weight
428.29
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
MBS3602492-01Eltanexor
A17207-25Eltanexor 25mg
A17207-50Eltanexor 50mg
A17207-500Eltanexor 500mg
A17207-100Eltanexor 100mg
A17207-5Eltanexor 5mg
A17207-1Eltanexor 1mg
A17207-10Eltanexor 10mg
A17207-2Eltanexor 2mg
C13392-1gEltanexor (KPT-8602)

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