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L002

CAT: 0013-GTR19177173-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177173-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L002 is a potent, cell-permeable, and reversible inhibitor of the p300 acetyltransferase (KAT3B), competitively binding its acetyl-CoA pocket with an IC50 of 1.98 μM. It blocks histone and p53 acetylation and STAT3 activation, showing research utility in studying cardiac hypertrophy and fibrosis in both cellular and animal models.
CAS Number
321695-57-2
Product Name Alternative
Histone Acetyltransferase, histone, HistoneAcetyltransferase, Inhibitor, GCN5, HAT, HATs, fibrosis, PCAF, inhibit, KAT3B, L 002, L002, L-002, cardiac, acetylation, p300, STAT
Field of Research
Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
95.66% (May vary between batches)
Solubility
DMSO:60 mg/mL (186.71 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.22 mM)
Smiles
COc1ccc (cc1) S (=O) (=O) ON=C1C=C (C) C (=O) C (C) =C1
Molecular Formula
C15H15NO5S
Molecular Weight
321.35
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
B7739-10L002
B1580-25OG-L002
E0405-5mgL002 (NSC764414)
A20336-100L002 100mg
A20336-25L002 25mg

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