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Samuraciclib hydrochloride

CAT: 0013-GTR19176852-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19176852-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Samuraciclib hydrochloride is a potent, orally bioavailable and selective CDK7 inhibitor (IC50=41 nM) . It demonstrates anti-proliferative activity in breast cancer cell lines (GI50 0.2-0.3 μM) and has shown antitumor efficacy in preclinical in vivo studies.
CAS Number
1805789-54-1
Product Name Alternative
CT7001, CT-7001, CT7001 hydrochloride, CT7001 Hydrochloride, CT-7001 Hydrochloride, CT 7001, CT 7001 Hydrochloride, cycle, Cyclin dependent kinase, deregulation, CDK4/Cyc D1, cdk2/cyclin A, CDK2/cyclinA, CDK5/p35NCK, CDK6/cycD1, CDK7, CDK7/cyclinH, CDK7/cyclin H, CDK9/CycT1, CDK, CDK1/cyc A, Apoptosis, anti-tumor, ATP-competitive, Asp155, arrest, non-covalent, inhibit, ICEC 0942, ICEC 0942 Hydrochloride, ICEC0942, ICEC-0942, ICEC0942 hydrochloride, ICEC0942 Hydrochloride, ICEC-0942 Hydrochloride, Inhibitor, Samuraciclib, Samuraciclib hydrochloride, Samuraciclib Hydrochloride, PolII, phosphorylates
Field of Research
Cell Biology
Purity
≥98% (May vary between batches)
Solubility
H2O:55 mg/mL (127.62 mM) ; DMSO:150 mg/mL (348.05 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.64 mM)
Smiles
Cl.CC (C) c1cnn2c (NCc3ccccc3) cc (NC[C@H]3CCNC[C@@H]3O) nc12
Molecular Formula
C22H31ClN6O
Molecular Weight
430.97
Storage Conditions
-20°C
Notes
For research use only.

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