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FG 7142

CAT: 0013-GTR19176711-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19176711-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FG 7142 is a benzodiazepine inverse agonist with high affinity for α1 subunit-containing GABAA receptors (Ki=91 nM) . It modulates GABA-induced chloride flux and has been used in research to study anxiety-related neurochemistry, including in vivo effects on cortical tyrosine hydroxylation and β-adrenoceptor upregulation in mice.
CAS Number
78538-74-6
Product Name Alternative
Dopaminergic, FG 7142, FG7142, FG-7142, GABAReceptor, GABA Receptor, GABAA, GABAA receptor, Gamma-aminobutyric acid Receptor, Inhibitor, inhibit, inverse agonist, nucleus accumben, LSU 65, LSU65, LSU-65, ZK39106, ZK-39106, ZK 39106, tyrosine hydroxylase, γ-Aminobutyric acid Receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.75% (May vary between batches)
Solubility
DMSO:30 mg/mL (133.19 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.88 mM)
Smiles
CNC (=O) c1cc2c (cn1) [nH]c1ccccc21
Molecular Formula
C13H11N3O
Molecular Weight
225.25
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

FG-7142

N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide is a member of beta-carbolines.

CAS Number78538-74-6
PubChem CID4375
IUPAC NameN-methyl-9H-pyrido[3,4-b]indole-3-carboxamide
Molecular FormulaC13H11N3O
Molecular Weight225.25
XLogP2.8
Topological Polar Surface Area57.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count17
Formal Charge0
Complexity307
SMILES
CNC(=O)C1=NC=C2C(=C1)C3=CC=CC=C3N2
InChI
InChI=1S/C13H11N3O/c1-14-13(17)11-6-9-8-4-2-3-5-10(8)16-12(9)7-15-11/h2-7,16H,1H3,(H,14,17)
InChIKey
QMCOPDWHWYSJSA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of FG-7142
CAS: 78538-74-6
CID: 4375
Formula: C13H11N3O
MW: 225.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight225.25
XLogP32.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass225.090211983
Monoisotopic Mass225.090211983
Topological Polar Surface Area57.8 Ų
Heavy Atom Count17
Formal Charge0
Complexity307
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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