Products for Research Use Only

MMAF-OMe

CAT: 0013-GTR19176633-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19176633-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MMAF-OMe is a potent antimitotic agent and a key cytotoxin used in antibody-drug conjugates (ADCs) . It demonstrates sub-nanomolar cytotoxicity against various cancer cell lines in vitro and is employed in oncology research for evaluating ADC efficacy in both cellular and animal models.
CAS Number
863971-12-4
Product Name Alternative
ADC Cytotoxin, ADC Payload, ADCCytotoxin, MMAF OMe, MMAFOMe, MMAF-OMe, inhibit, Monomethyl auristatin F methyl ester, Inhibitor
Purity
98.15% (May vary between batches)
Solubility
5% DMSO+95% Saline:4 mg/mL (5.36 mM) ; DMSO:99 mg/mL (132.71 mM)
Smiles
CC[C@H] (C) [C@@H] ([C@@H] (CC (=O) N1CCC[C@H]1[C@H] (OC) [C@@H] (C) C (=O) N[C@@H] (Cc1ccccc1) C (=O) OC) OC) N (C) C (=O) [C@@H] (NC (=O) [C@@H] (NC) C (C) C) C (C) C
Molecular Formula
C40H67N5O8
Molecular Weight
745.99
Storage Conditions
-20°C
Notes
For research use only.