Products for Research Use Only
RegisterLogin

ORM-15341

CAT: 0013-GTR19177179-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19177179-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ORM-15341 is a potent full antagonist of the human androgen receptor (hAR), exhibiting an IC50 of 38 nM in cellular transactivation assays. This compound is a valuable research tool for investigating AR function in prostate cancer models and other hormone-dependent pathways, both in vitro and in vivo.
CAS Number
1297537-33-7
Product Name Alternative
ORM15341, ORM-15341, ORM 15341, inhibit, Inhibitor, AndrogenReceptor, Androgen Receptor
Field of Research
Metabolism Research
Purity
98.01% (May vary between batches)
Solubility
DMSO:100 mg/mL (252 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.08 mM)
Smiles
C[C@@H] (Cn1ccc (n1) -c1ccc (C#N) c (Cl) c1) NC (=O) c1cc ([nH]n1) C (C) =O
Molecular Formula
C19H17ClN6O2
Molecular Weight
396.83
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

(S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide

Ketodarolutamide, a nonsteroidal antiandrogen (NSAA), is the major active metabolite of [darolutamide].

CAS Number1297537-33-7
PubChem CID52919826
IUPAC Name3-acetyl-N-[(2S)-1-[3-(3-chloro-4-cyanophenyl)pyrazol-1-yl]propan-2-yl]-1H-pyrazole-5-carboxamide
Molecular FormulaC19H17ClN6O2
Molecular Weight396.8
XLogP2.2
Topological Polar Surface Area116
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count28
Formal Charge0
Complexity637
SMILES
C[C@@H](CN1C=CC(=N1)C2=CC(=C(C=C2)C#N)Cl)NC(=O)C3=CC(=NN3)C(=O)C
InChI
InChI=1S/C19H17ClN6O2/c1-11(22-19(28)18-8-17(12(2)27)23-24-18)10-26-6-5-16(25-26)13-3-4-14(9-21)15(20)7-13/h3-8,11H,10H2,1-2H3,(H,22,28)(H,23,24)/t11-/m0/s1
InChIKey
GMBPVBVTPBWIKC-NSHDSACASA-N
Chemical Structure
2D Structure
2D structure of (S)-5-acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1H-pyrazole-3-carboxamide
CAS: 1297537-33-7
CID: 52919826
Formula: C19H17ClN6O2
MW: 396.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight396.8
XLogP32.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass396.1101515
Monoisotopic Mass396.1101515
Topological Polar Surface Area116 Ų
Heavy Atom Count28
Formal Charge0
Complexity637
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19219692-01(+) -ORM-10921
GTR19205241-01ORM-10103
GTR19196848-01ORM-10921
GTR19208198-01ORM-13070
GTR19205240-01ORM-10962
GTR19196847-01ORM-3819
GTR18775006-01ORM-5029 Antibody
GTR19154183-01BGC20-1531 hydrochloride
GTR19185345-01BGC-20-1531 free base
GTR19096602-01Recombinant Saccharomyces monacensis Protein ORM1 (ORM1)

Alternative Products

CatalogName
MBS3601200-01ORM-15341
A12312-25Ketodarolutamide (ORM-15341) 25mg
A12312-5Ketodarolutamide (ORM-15341) 5mg
A12312-100Ketodarolutamide (ORM-15341) 100mg
A12312-50Ketodarolutamide (ORM-15341) 50mg
A12312-10Ketodarolutamide (ORM-15341) 10mg
A12312-1Ketodarolutamide (ORM-15341) 1mg
A12312-10mM-DKetodarolutamide (ORM-15341) 10mM * 1mL in DMSO
NUA84728-01ORM-10103
NFB92698-01ORM-10962

Popular Products