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Oxidopamine hydrochloride

CAT: 0013-GTR19177090-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19177090-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is a selective dopaminergic neurotoxin that induces inflammation via COX-2 activation. It is extensively used to model Parkinson's disease pathology in vivo and to study neuroinflammation and neuronal death in vitro.
CAS Number
28094-15-7
Product Name Alternative
P38 MAPK, Oxidopamine, Oxidopamine hydrochloride, Oxidopamine Hydrochloride, p-p38, PGE synthase, PGE2, SH-SY5Y cells, Prostaglandin E synthase, 6-OHDA, 6-OHDA Hydrochloride, 6-OHDA hydrochloride, 6-Hydroxydopamine, 6-Hydroxydopamine Hydrochloride, 6-Hydroxydopamine hydrochloride, Autophagy, attention-deficit hyperactivity disorder, Apoptosis, Caspase, Dopamine Receptor, dopamine, DopamineReceptor, COX, Cyclooxygenase, Mitochondrial Autophagy, PC12 cells, Parkinson's disease, Neuro-2a cells, neurotoxicity, Mitophagy, inhibit, Lesch-Nyhan syndrome, Interleukin Related, Inhibitor
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery
Purity
96.17% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.73 mM) ; H2O:62.49 mg/mL (303.88 mM) ; DMSO:62.49 mg/mL (303.88 mM)
Smiles
Cl.NCCc1cc (O) c (O) cc1O
Molecular Formula
C8H12ClNO3
Molecular Weight
205.64
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

6-Hydroxydopamine hydrochloride

Oxidopamine Hydrochloride is an organic molecular entity.

CAS Number28094-15-7
PubChem CID160157
IUPAC Name5-(2-aminoethyl)benzene-1,2,4-triol;hydrochloride
Molecular FormulaC8H12ClNO3
Molecular Weight205.64
Topological Polar Surface Area86.7
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count13
Formal Charge0
Complexity142
SMILES
C1=C(C(=CC(=C1O)O)O)CCN.Cl
InChI
InChI=1S/C8H11NO3.ClH/c9-2-1-5-3-7(11)8(12)4-6(5)10;/h3-4,10-12H,1-2,9H2;1H
InChIKey
QLMRJHFAGVFUAC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 6-Hydroxydopamine hydrochloride
CAS: 28094-15-7
CID: 160157
Formula: C8H12ClNO3
MW: 205.64
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight205.64
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass205.0505709
Monoisotopic Mass205.0505709
Topological Polar Surface Area86.7 Ų
Heavy Atom Count13
Formal Charge0
Complexity142
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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