Products for Research Use Only

Etidronic acid

CAT: 0013-GTR19176251-01Size: 500 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19176251-01Size:500 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Etidronic acid (HEDP) is a bisphosphonate compound that modulates calcium metabolism by inhibiting pathological calcification and reducing the rate of bone resorption and turnover. It is widely used in osteoporosis research and in vitro studies of mineralization, as well as in vivo models of ectopic bone formation.
CAS Number
2809-21-4
Product Name Alternative
Protein tyrosine phosphatase (PTP), V-type proton ATPase catalytic subunit, Apoptosis, arterial calcification, osteoporosis, inhibit, Paget's disease, Etidronic acid, Etidronate, HAP, MCF-7, Inhibitor, HEDP, HEDPA
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery
Purity
≥95% (May vary between batches)
Solubility
DMSO:45 mg/mL (218.41 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.71 mM)
Smiles
C (P (=O) (O) O) (P (=O) (O) O) (C) O
Molecular Formula
C2H8O7P2
Molecular Weight
206.03
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Etidronic Acid

Etidronic acid is a 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces. It has a role as an antineoplastic agent, a chelator and a bone density conservation agent. It is a conjugate acid of an etidronic acid(2-).

CAS Number2809-21-4
PubChem CID3305
IUPAC Name(1-hydroxy-1-phosphonoethyl)phosphonic acid
Molecular FormulaC2H8O7P2
Molecular Weight206.03
XLogP-3.7
Topological Polar Surface Area135
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Heavy Atom Count11
Formal Charge0
Complexity211
SMILES
CC(O)(P(=O)(O)O)P(=O)(O)O
InChI
InChI=1S/C2H8O7P2/c1-2(3,10(4,5)6)11(7,8)9/h3H,1H3,(H2,4,5,6)(H2,7,8,9)
InChIKey
DBVJJBKOTRCVKF-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Etidronic Acid
CAS: 2809-21-4
CID: 3305
Formula: C2H8O7P2
MW: 206.03
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight206.03
XLogP3-3.7
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass205.97452659
Monoisotopic Mass205.97452659
Topological Polar Surface Area135 Ų
Heavy Atom Count11
Formal Charge0
Complexity211
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Popular Products