Products for Research Use Only
RegisterLogin

3CAI

CAT: 0013-GTR19175510-03Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19175510-03Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
3CAI is a potent and specific inhibitor of AKT1 and AKT2. It demonstrates efficacy in vitro by suppressing downstream mTOR and GSK3β signaling, leading to growth inhibition and apoptosis in colon cancer cell models. Its application extends to research in oncology and signal transduction pathways.
CAS Number
28755-03-5
Product Name Alternative
3CAI, Akt, Akt1, Akt2, Inhibitor, inhibit, Protein kinase B, PKB
Field of Research
Signal Transduction
Purity
98.13% (May vary between batches)
Solubility
DMSO:246 mg/mL (1270.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (25.82 mM)
Smiles
ClCC (=O) c1c[nH]c2ccccc12
Molecular Formula
C10H8ClNO
Molecular Weight
193.63
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

3-Chloroacetylindole
CAS Number28755-03-5
PubChem CID152961
IUPAC Name2-chloro-1-(1H-indol-3-yl)ethanone
Molecular FormulaC10H8ClNO
Molecular Weight193.63
XLogP2.7
Topological Polar Surface Area32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Heavy Atom Count13
Formal Charge0
Complexity207
SMILES
C1=CC=C2C(=C1)C(=CN2)C(=O)CCl
InChI
InChI=1S/C10H8ClNO/c11-5-10(13)8-6-12-9-4-2-1-3-7(8)9/h1-4,6,12H,5H2
InChIKey
LLZQFAXTCYDVTR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-Chloroacetylindole
CAS: 28755-03-5
CID: 152961
Formula: C10H8ClNO
MW: 193.63
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight193.63
XLogP32.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass193.0294416
Monoisotopic Mass193.0294416
Topological Polar Surface Area32.9 Ų
Heavy Atom Count13
Formal Charge0
Complexity207
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
C17877-5mg3CAI
A20924-253CAI 25mg
A20924-503CAI 50mg
A20924-5003CAI 500mg
A20924-103CAI 10mg
A20924-2003CAI 200mg
A20924-1003CAI 100mg
A20924-53CAI 5mg
A20924-10mM-D3CAI 10mM * 1mL in DMSO
217170Akt Inhibitor XIX, 3CAI (2-Chloro-1- (1H-indol-3-yl) -ethanone, 3-Chloroacetyl-indole)

Popular Products