Products for Research Use Only

DG-041

CAT: 0013-GTR19175384-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19175384-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DG-041 is a potent and selective EP3 receptor antagonist, exhibiting IC50 values of 4.6 nM and 8.1 nM in binding and functional assays, respectively. It effectively inhibits PGE2-mediated platelet aggregation in vitro and demonstrates blood-brain barrier permeability, supporting its utility in researching thrombosis and neuroinflammatory models.
CAS Number
861238-35-9
Product Name Alternative
Blood-brain, barrier, atherothrombosis, atherosclerotic, DG041, DG-041, DG 041, infarction, Myocardial, inhibit, EP3 receptor, EP3, Inhibitor, stroke, plaque, Prostaglandin Receptor, ProstaglandinReceptor
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
97.25% (May vary between batches)
Solubility
DMSO:55 mg/mL (92.86 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.38 mM)
Smiles
Cc1cn (Cc2ccc (Cl) cc2Cl) c2c (\C=C\C (=O) NS (=O) (=O) c3cc (Cl) c (Cl) s3) cc (F) cc12
Molecular Formula
C23H15Cl4FN2O3S2
Molecular Weight
592.32
Storage Conditions
-20°C
Notes
For research use only.