C 87

CAT: 0013-GTR19175077-01Size: 50 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19175077-01Size:50 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

C 87 is a small molecule that directly inhibits TNF-α by binding to it, blocking TNF-α-induced cytotoxicity (IC50 = 8.73 μM) and downstream signaling. It is a useful research tool for studying TNF-α-mediated inflammatory and autoimmune pathways in both cellular and animal models.

CAS Number

332420-90-3

Product Name Alternative

Inhibitor, inhibit, C 87, C87, C-87, TNF Receptor, TNFR, TNFα-induced cytotoxicity, TNF-α, Tumor Necrosis Factor Receptor

Field of Research

Cell Biology

Purity

≥98% (May vary between batches)

Solubility

DMSO:5.06 mg/mL (10.06 mM)

Smiles

[O-][N+] (=O) c1cc (N\N=C2\C (=O) N (N=C2c2ccccc2) c2nc (cs2) -c2ccccc2) ccc1Cl

Molecular Formula

C24H15ClN6O3S

Molecular Weight

502.93

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

TNFalpha-IN-C87

CAS Number	332420-90-3
PubChem CID	4016403
IUPAC Name	4-[(4-chloro-3-nitrophenyl)diazenyl]-5-phenyl-2-(4-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-3-one
Molecular Formula	C24H15ClN6O3S
Molecular Weight	502.9
XLogP	6.6
Topological Polar Surface Area	144
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Heavy Atom Count	35
Formal Charge	0
Complexity	855

SMILES

C1=CC=C(C=C1)C2=CSC(=N2)N3C(=O)C(=C(N3)C4=CC=CC=C4)N=NC5=CC(=C(C=C5)Cl)[N+](=O)[O-]

InChI

InChI=1S/C24H15ClN6O3S/c25-18-12-11-17(13-20(18)31(33)34)27-28-22-21(16-9-5-2-6-10-16)29-30(23(22)32)24-26-19(14-35-24)15-7-3-1-4-8-15/h1-14,29H

InChIKey

HTEQQWJUYYUNQG-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 332420-90-3

CID: 4016403

Formula: C24H15ClN6O3S

MW: 502.9

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	502.9
XLogP3	6.6
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Exact Mass	502.0614872
Monoisotopic Mass	502.0614872
Topological Polar Surface Area	144 Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	855
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
GTR19068088-01	C-Peptide (57-87), human
GTR19208382-01	H-87
GTR19230170-01	EGFR-IN-87
GTR19170951-01	XMD8-87
GTR19241121-01	LXQ-87
GTR19258789-01	α-Glucosidase-IN-87
GTR19258401-01	AChE-IN-87
GTR19249525-01	HDAC-IN-87
GTR19164215-01	XMD8-87
GTR18890617	Human C-Peptide (57-87) peptide

Alternative Products

Catalog	Name
TBI3024-25MG	Ac-Leu-Leu-Nle-CHO (ALLN), Calpain inhibitor
TBS10340-0.5MG	InVivo Mouse IgG1 Isotype Control Antibody
TBS10338-0.5MG	InVivo Anti-Mouse CD161/KLRB1/NK1.1 Antibody
TBS10336-1MG	InVivoMAb Anti-Human Flt3 ligand/FLT3LG Antibody
TBS10334-0.5MG	InVivo Anti-Human CDH17/Cadherin-17 Monoclonal Antibody
TBS10333-1MG	InVivo Anti-Phosphotyrosine Monoclonal Antibody
TBS42064-100	Clostridium butyricum qPCR Detection Kit
TBI5887-25MG	Ro 5-3335, RUNX1 inhibitor
TBI5778-5MG	SBI-797812, NAMPT activator
TBI5468-25MG	Pyrintegrin, ß1-integrin agonist

C 87

Chemical Information

Related Products

Alternative Products

Popular Products