Products for Research Use Only
RegisterLogin

VU-29

CAT: 0013-GTR19175015-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19175015-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
VU-29 is a potent and selective positive allosteric modulator of the mGlu5 receptor, exhibiting an EC50 of 9 nM. Its selectivity over other mGluR subtypes makes it a valuable research tool for investigating mGlu5 function in neuropharmacology, synaptic plasticity, and related in vitro and in vivo models.
CAS Number
890764-36-0
Product Name Alternative
Allosteric, hippocampal, Inhibitor, inhibit, mGluR, Metabotropic glutamate receptors, LTD, LTP, rat, potentiator, VU29, VU-29, VU 29
Field of Research
Neuroscience
Purity
99.47% (May vary between batches)
Solubility
DMSO:25 mg/mL (65.04 mM)
Smiles
N (C (=O) C1=CC=C (N (=O) =O) C=C1) C=2N (N=C (C2) C3=CC=CC=C3) C4=CC=CC=C4
Molecular Formula
C22H16N4O3
Molecular Weight
384.39
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-(1,3-diphenyl-1H-pyrazolo-5-yl)-4-nitrobenzamide

an mGluR5 positive allosteric modulator; structure in first source

CAS Number890764-36-0
PubChem CID11610682
IUPAC NameN-(1,3-diphenylpyrazol-5-yl)-4-nitrobenzamide
Molecular FormulaC22H16N4O3
Molecular Weight384.4
XLogP4.6
Topological Polar Surface Area92.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count29
Formal Charge0
Complexity561
SMILES
C1=CC=C(C=C1)C2=NN(C(=C2)NC(=O)C3=CC=C(C=C3)[N+](=O)[O-])C4=CC=CC=C4
InChI
InChI=1S/C22H16N4O3/c27-22(17-11-13-19(14-12-17)26(28)29)23-21-15-20(16-7-3-1-4-8-16)24-25(21)18-9-5-2-6-10-18/h1-15H,(H,23,27)
InChIKey
KIALCSMRIHRFPL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(1,3-diphenyl-1H-pyrazolo-5-yl)-4-nitrobenzamide
CAS: 890764-36-0
CID: 11610682
Formula: C22H16N4O3
MW: 384.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight384.4
XLogP34.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass384.12224039
Monoisotopic Mass384.12224039
Topological Polar Surface Area92.7 Ų
Heavy Atom Count29
Formal Charge0
Complexity561
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19161446-01VU 0361737
GTR19216724-01VU 0255035
GTR19196186-01VU 0469650
GTR19166266-01VU 0240551
GTR19166147-01VU 0238429
GTR19163962-01VU 0469381
GTR19219786-01VU 0546110
GTR19200703-01VU 0285683
GTR19200700-01VU 0360223
GTR19160957-01VU 0364439

Alternative Products

CatalogName
T23515-01VU-29
MBS3612310-01VU 29
B7329-50VU 0155041
B7487-50VU 0255035
B5569-10VU 0285683
A2623-100VU 0364439
B1630-5VU 0361737
B7434-5VU 0155069
JRA35128-01VU 152100
IYB22239VU 0365114

Popular Products