CSNK1A1 + CSNK1A1L Recombinant Rabbit Monoclonal Antibody [PSH04-58]

• Description:

  Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2 (By similarity). May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. Acts as an inhibitor of NLRP3 inflammasome assembly by mediating phosphorylation of NLRP3 (By similarity).

• Product Name Alternative:

  Casein kinase 1 alpha 1 antibody Casein kinase I isoform alpha antibody CK1 antibody CK1A antibody CKI alpha antibody CKI-alpha antibody CKIa antibody Clock regulator kinase antibody Csnk1a1 antibody Down regulated in lung cancer antibody HLCDGP1 antibody KC1A_HUMAN antibody PRO2975 antibody Casein kinase 1, alpha 1 like antibody casein kinase 1, alpha 1-like antibody Casein kinase I alpha S like antibody Casein kinase I isoform alpha like antibody CK1 antibody CKI alpha like antibody MGC33182 antibody OTTHUMP00000018267 antibody RP11 532O21.2 antibody

• Abbreviation:

  CSNK1A1, CSNK1A1L

• Swiss Prot:

  P48729 Human, Q8N752 Human, Q8BK63 Mouse, P97633 Rat

• Cellular Locus:

  Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Chromosome, centromere, kinetochore, Nucleus speckle, cilium basal body, spindle.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein within human CSNK1A1 aa 1-337 / 337.

• Isotype:

  IgG

• Clone:

  PSH04-58

• Conjugation:

  Non-conjugated

• Type:

  Recombinant Rabbit monoclonal Antibody

• Applications:

  WB, IF-Cell, IHC-P, FC, IP

• Positive Control:

  HCT 116 cell lysate, HeLa cell lysate, HEK-293 cell lysate, MCF7 cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, PC-12 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, mouse kidney tissue lysate, rat kidney tissue lysate, mouse spleen tissue lysate, rat spleen tissue lysate, human colon cancer tissue, human tonsil tissue, human brain tissue, mouse brain tissue, rat brain tissue, HCT 116.

• Concentration:

  1 mg/mL

• Dilution:

  WB: 1:2,000 ;IF-Cell: 1:500 ;IHC-P: 1:1,000 ;FC: 1:1,000 ;IP: 1-2μg/sample

• Purity:

  Protein A affinity purified.

• Form:

  Liquid

• Buffer:

  PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• Molecular Weight:

  Predicted band size: 39 kDa

• Storage Conditions:

  Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

• Recombinant Antibody:

  Yes

• CAS Number:

  9000-83-3