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IC261

CAT: 0013-GTR19174871-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174871-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IC261 (SU-5607) is a selective casein kinase 1 (CK1) inhibitor with an IC50 of 16 μM, which is significantly more potent than its activity against Cdk5 (IC50 4.5 mM) . It activates the mitotic checkpoint and is widely used in vitro to study cell cycle regulation, apoptosis, and circadian rhythms.
CAS Number
186611-52-9
Product Name Alternative
CDK5, CK1, Casein Kinase, CaseinKinase, Apoptosis, inhibit, Inhibitor, IC-261, IC261, IC 261, SU 5607, SU5607, SU-5607
Field of Research
Cell Biology, Metabolism Research, Stem Cell & Developmental Biology
Purity
98.77% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.42 mM) ; DMSO:70 mg/mL (224.84 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
COc1cc (OC) c (\C=C2\C (=O) Nc3ccccc23) c (OC) c1
Molecular Formula
C18H17NO4
Molecular Weight
311.33
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
B6108-10IC261

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