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DDD85646

CAT: 0013-GTR19174703-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174703-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DDD85646 is a potent and selective inhibitor of Trypanosoma brucei N-myristoyltransferase (TbNMT), exhibiting sub-nanomolar binding affinity (Ki=1.44 nM) and potent activity against the parasite (EC50=2 nM) . It shows selectivity over human NMT (IC50=4 nM), making it a valuable chemical probe for studying trypanosomatid biology and for anti-parasitic drug discovery research in both in vitro and in vivo models.
CAS Number
1215010-55-1
Product Name Alternative
DNA/RNA Synthesis, African trypanosomiasis, inhibit, Parasite, NMT, N-myristoyltransferase, N-myristoyltransferase-1 (NMT-1), Inhibitor, DDD85646, DDD-85646, DDD 85646, trypanosoma brucei
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology
Purity
97.80% (May vary between batches)
Solubility
DMSO:95 mg/mL (191.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.66 mM)
Smiles
Cc1nn (C) c (C) c1NS (=O) (=O) c1c (Cl) cc (cc1Cl) -c1ccnc (c1) N1CCNCC1
Molecular Formula
C21H24Cl2N6O2S
Molecular Weight
495.43
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
E5974-1gDDD85646

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