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Avasimibe

CAT: 0013-GTR19174640-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174640-01Size:10 mg
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Description
Avasimibe (PD-148515) is an orally active ACAT inhibitor (IC50: 3.3 μM) that reduces arterial cholesterol deposition. It also inhibits CYP2C9, 1A2, and 2C19 isoenzymes. This compound is used in research on atherosclerosis and drug metabolism, with applications in both in vitro enzymatic assays and in vivo models of hyperlipidemia.
CAS Number
166518-60-1
Product Name Alternative
SOAT, mono- acylglycerol acyltransferase, Inhibitor, inhibit, PD148515, PD-148515, PD 148515, orally, Avasimibe, active, Acyltransferase, acyl-CoA:cholesterol acyltransferase, ACAT1, ACAT, ACAT2, CYP1A2, CYP2C19, CYP2C9, Diglyceride acyltransferase, Diacylglycerol acyltransferase, CI 1011, CI-1011, CI1011
Field of Research
Metabolism Research
Purity
>98%
Bioactivity
ACAT inhibitor
Form
Powder
Solubility
Ethanol:2 mg/mL (3.99 mM) ;10% DMSO+90% Corn Oil:5 mg/mL (9.97 mM) ; DMSO:102 mg/mL (203.3 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CC (C) c1cc (C (C) C) c (CC (=O) NS (=O) (=O) Oc2c (cccc2C (C) C) C (C) C) c (c1) C (C) C
Molecular Formula
C29H43NO4S
Molecular Weight
501.72
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
A4318-200Avasimibe

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