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GSK3145095

CAT: 0013-GTR19174474-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174474-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK3145095 is a potent, orally bioavailable RIPK1 inhibitor (IC50 = 5 nM) . It has demonstrated immunomodulatory and anti-cancer activity in preclinical studies, including in vitro assays and in vivo models of pancreatic cancer and systemic inflammation.
CAS Number
1622849-43-7
Product Name Alternative
Inhibitor, inhibit, GSK3145095, GSK-3145095, GSK 3145095, RIP kinase, RIPK, RIP1 kinase, RIP1, RIPkinase, Receptor-interacting protein kinases
Field of Research
Cell Biology, Signal Transduction
Purity
99.50% (May vary between batches)
Solubility
DMSO:245 mg/mL (616.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.58 mM)
Smiles
Fc1cc (F) c2NC (=O) [C@H] (CCc2c1) NC (=O) c1n[nH]c (Cc2ccccc2) n1
Molecular Formula
C20H17F2N5O2
Molecular Weight
397.38
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
BA3501-5.1GSK3145095
A19427-50GSK3145095 50mg
A19427-10GSK3145095 10mg
A19427-100GSK3145095 100mg
A19427-25GSK3145095 25mg
A19427-5GSK3145095 5mg
A19427-1GSK3145095 1mg
A19427-10mM-DGSK3145095 10mM * 1mL in DMSO

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