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Tandutinib

CAT: 0013-GTR19174260-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174260-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tandutinib (MLN518) is a potent and selective FLT3 inhibitor (IC50 = 0.22 μM) with additional activity against c-Kit and PDGFR. It demonstrates significant selectivity over CSF-1R, FGFR, EGFR, and KDR. This small molecule is a valuable research tool for studying FLT3-driven hematological cancers in both cellular and animal models.
CAS Number
387867-13-2
Product Name Alternative
CT 53518, CT53518, CT-53518, CSF-1R, CSF1R, Cluster of differentiation antigen 135, CD135, CD117, c-Kit, cKit, Acute, blood-brain, Apoptosis, barrier, autophosphorylation, NSC 726292, Inhibitor, myelogenous, inhibit, MLN518, MLN-518, MLN 518, NSC726292, NSC-726292, PDGFR, Platelet-derived growth factor receptor, FLT3-ITD, FLT3, Fms like tyrosine kinase 3, MAP, leukemia, Src, SCFR, Tandutinib, PI3, PDGFRβ
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
≥98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.55 mM) ; Ethanol:6 mg/mL (10.66 mM) ; DMSO:50 mg/mL (88.86 mM)
Smiles
O (C) C1=CC=2C (=NC=NC2C=C1OCCCN3CCCCC3) N4CCN (C (NC5=CC=C (OC (C) C) C=C5) =O) CC4
Molecular Formula
C31H42N6O4
Molecular Weight
562.7
Storage Conditions
-20°C
Notes
For research use only.

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