ETS1 (Marker of Tumor Metastasis)

ETS1 (Marker of Tumor Metastasis)

• Gene Name: [ETS1]
• NCBI Gene ID: 2113
• Reactivity: Human. Others not known.
• Storage Conditions: Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator. The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells. ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.
• Other Gene Names: [ETS1; ETS1; p54; ETS-1; EWSR2; c-ets-1; EWSR2]
• Short Name: [ETS1]
• Other Product Names: [protein C-ets-1 isoform 1; Protein C-ets-1; protein C-ets-1; ETS proto-oncogene 1, transcription factor; p54]
• NCBI GI Number: 219689118
• NCBI Accession Number: NP_001137292.1
• NCBI GB Accession Number: NM_001143820.1
• Uniprot Accession Number: P14921