ETS1 (Marker of Tumor Metastasis)

• Gene Name:

  [ETS1]

• NCBI Gene ID:

  2113

• Reactivity:

  Human. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator. The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells. ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.

• Other Gene Names:

  [ETS1; ETS1; p54; ETS-1; EWSR2; c-ets-1; EWSR2]

• Short Name:

  [ETS1]

• Other Product Names:

  [protein C-ets-1 isoform 1; Protein C-ets-1; protein C-ets-1; ETS proto-oncogene 1, transcription factor; p54]

• NCBI GI Number:

  219689118

• NCBI Accession Number:

  NP_001137292.1

• NCBI GB Accession Number:

  NM_001143820.1

• Uniprot Accession Number:

  P14921