Products for Research Use Only
RegisterLogin

SB-222200

CAT: 0013-GTR19174175-06Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19174175-06Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SB-222200 is a potent and selective competitive antagonist of the human neurokinin-3 (NK-3) receptor, exhibiting a Ki of 4.4 nM. It is a valuable research tool for studying NK-3 receptor function in both in vitro assays and in vivo models related to reproduction, anxiety, and gastrointestinal motility.
CAS Number
174635-69-9
Product Name Alternative
Inhibitor, inhibit, NK receptor, NK3, NK-3R, NKB, Neurokinin receptor, neurokinin-B, Neurokininreceptor, Neurokinin Receptor, nervous, central, CNS, disorders, penetrant, SB 222200, SB222200, SB-222200, system, Tachykinin receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.51 mM) ; DMSO:100 mg/mL (262.83 mM)
Smiles
C (N[C@@H] (CC) C1=CC=CC=C1) (=O) C=2C3=C (N=C (C2C) C4=CC=CC=C4) C=CC=C3
Molecular Formula
C26H24N2O
Molecular Weight
380.48
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

SB 222200

3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]-4-quinolinecarboxamide is a member of quinolines.

CAS Number174635-69-9
PubChem CID6604009
IUPAC Name3-methyl-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Molecular FormulaC26H24N2O
Molecular Weight380.5
XLogP5.9
Topological Polar Surface Area42
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Heavy Atom Count29
Formal Charge0
Complexity523
SMILES
CC[C@@H](C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)C
InChI
InChI=1S/C26H24N2O/c1-3-22(19-12-6-4-7-13-19)28-26(29)24-18(2)25(20-14-8-5-9-15-20)27-23-17-11-10-16-21(23)24/h4-17,22H,3H2,1-2H3,(H,28,29)/t22-/m0/s1
InChIKey
MQNYRKWJSMQECI-QFIPXVFZSA-N
Chemical Structure
2D Structure
2D structure of SB 222200
CAS: 174635-69-9
CID: 6604009
Formula: C26H24N2O
MW: 380.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight380.5
XLogP35.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count5
Exact Mass380.188863393
Monoisotopic Mass380.188863393
Topological Polar Surface Area42 Ų
Heavy Atom Count29
Formal Charge0
Complexity523
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19153626-01SB-269970, SB 269970
GTR19156054-01SB 204990
GTR19160328-01SB-756050
GTR19234665-01SB 206553
GTR19224296-01SB 211475
GTR19218772-01SB-649701
GTR19204834-01SB-277011
GTR19200858-01SB 268262
GTR19200853-01SB 706504
GTR19199673-01SB-429201

Alternative Products

CatalogName
MBS386104-01SB-222200
MBS130146-01SB 222200
A15230-25SB-222200 25mg
A15230-50SB-222200 50mg
A15230-5SB-222200 5mg
A15230-1SB-222200 1mg
A15230-100SB-222200 100mg
A15230-10SB-222200 10mg
A15230-10mM-DSB-222200 10mM * 1mL in DMSO
217783SB-277011-A Dihydrochloride (SB277011A, SB 277011A, Dopamine D3 Receptor Antagonist, SB-277011-A, SB-277011A)

Popular Products