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SB-265610

CAT: 0013-GTR19174173-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174173-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB-265610 (GSK-CXCR2) is a potent, nonpeptide allosteric antagonist of the CXCR2 receptor. It effectively inhibits CINC-1-induced calcium mobilization and neutrophil chemotaxis with IC50 values of 3.7 nM and 70 nM, respectively. This compound is a valuable research tool for studying CXCR2-mediated inflammatory responses in both cellular and animal models of disease.
CAS Number
211096-49-0
Product Name Alternative
Inhibitor, nonpeptide, inhibit, inflammation, neutrophil, GSK-CXCR2, healing, Delay, CXCR, CXCR2, CXC chemokine receptors, wound, recruitment, SB265610, SB-265610, SB 265610
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
97.67% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.6 mM) ; DMSO:66 mg/mL (184.79 mM)
Smiles
Brc1ccccc1NC (=O) Nc1ccc (C#N) c2nn[nH]c12
Molecular Formula
C14H9BrN6O
Molecular Weight
357.16
Storage Conditions
-20°C
Notes
For research use only.

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