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Tazemetostat hydrobromide

CAT: 0013-GTR19174115-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174115-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tazemetostat hydrobromide is a potent, selective inhibitor of EZH2 (Ki=2.5 nM) and EZH1 (IC50=392 nM), targeting the PRC2 complex. It is widely used in oncology research to study epigenetic mechanisms in vitro and has demonstrated antitumor efficacy in various preclinical in vivo models.
CAS Number
1467052-75-0
Product Name Alternative
Tazemetostat, Tazemetostat Hydrobromide, Tazemetostat hydrobromide, Rat EZH2, PRC2, cancer, E 7438, E 7438 Hydrobromide, E-7438, E7438, E7438 Hydrobromide, E-7438 hydrobromide, E-7438 Hydrobromide, inhibit, HistoneMethyltransferase, Histone Methyltransferase, Inhibitor, EZH2, EZH2 WT, EZH1, epigenetic, EPZ 6438, EPZ 6438 Hydrobromide, EPZ6438, EPZ-6438, EPZ6438 Hydrobromide, EPZ-6438 Hydrobromide, EPZ-6438 hydrobromide
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Purity
99.03% (May vary between batches)
Solubility
DMSO:102 mg/mL (156.05 mM)
Smiles
O=C (C1=CC (C2=CC=C (CN3CCOCC3) C=C2) =CC (N (CC) C4CCOCC4) =C1C) NCC5=C (C) C=C (C) NC5=O.[H]Br
Molecular Formula
C34H45BrN4O4
Molecular Weight
653.65
Storage Conditions
-20°C
Notes
For research use only.

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