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L-745870 trihydrochloride

CAT: 0013-GTR19174019-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174019-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-745870 trihydrochloride is a potent and selective dopamine D4 receptor antagonist with moderate affinity for 5-HT2 receptors, sigma sites, and α-adrenoceptors. It is a valuable research tool for investigating D4 receptor function in neuropsychiatric disorders and has been utilized in both in vitro binding assays and in vivo behavioral studies.
CAS Number
866021-03-6
Product Name Alternative
Brain-penetrant, Antipsychotic, 5HTReceptor, 5HT Receptor, 5-HT2, Adrenergic Receptor, AdrenergicReceptor, D4, D4-receptor, D3, D2, DopamineReceptor, Dopamine Receptor, orally, inhibit, L 745870, L 745870 trihydrochloride, L 745870 Trihydrochloride, Inhibitor, L-745,870, L-745,870 trihydrochloride, L-745,870 Trihydrochloride, L745870, L-745870, L745870 trihydrochloride, L745870 Trihydrochloride, L-745870 trihydrochloride, L-745870 Trihydrochloride, Sigmareceptor, Sigma receptor, α-adrenergic receptor, α-adrenoceptors
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.52% (May vary between batches)
Solubility
H2O:< 40 mg/mL; DMSO:50 mg/mL (114.62 mM)
Smiles
ClC1=CC=C (C=C1) N2CCN (CC2) CC3=CNC4=C3C=CC=N4.Cl.Cl.Cl
Molecular Formula
C18H22Cl4N4
Molecular Weight
436.21
Storage Conditions
-20°C
Notes
For research use only.

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