CD11a / Integrin alphaL / LFA-1 alpha Chain Mouse Monoclonal Antibody

CD11a / Integrin alphaL / LFA-1 alpha Chain Mouse Monoclonal Antibody

• CAS Number: 9007-83-4
• Gene Name: [ITGAL]
• NCBI Gene ID: 3683
• Reactivity: Human
• Storage Conditions: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.
• Other Gene Names: [ITGAL; ITGAL; CD11A; LFA-1; LFA1A; CD11A; LFA-1A]
• Short Name: [CD11a / Integrin alphaL / LFA-1 alpha Chain]
• Other Product Names: [integrin alpha-L isoform b; Integrin alpha-L; integrin alpha-L; integrin subunit alpha L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; CD_antigen: CD11a]
• NCBI GI Number: 167466217
• NCBI Accession Number: NP_001107852.1
• NCBI GB Accession Number: NM_001114380.1
• Uniprot Accession Number: P20701