Products for Research Use Only
RegisterLogin

S 14506 hydrochloride

CAT: 0013-GTR19173910-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19173910-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
S 14506 hydrochloride
CAS Number
286369-38-8
Product Name Alternative
S14506 Hydrochloride, S-14506 Hydrochloride, S 14506 hydrochloride, S 14506 Hydrochloride, 5HTReceptor, 5HT Receptor, 5-HT1A
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.50% (May vary between batches)
Solubility
DMSO:200 mg/mL (450.51 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cl.COc1ccc2cccc (N3CCN (CCNC (=O) c4ccc (F) cc4) CC3) c2c1
Molecular Formula
C24H27ClFN3O2
Molecular Weight
443.94
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Benzamide, 4-fluoro-N-(2-(4-(7-methoxy-1-naphthalenyl)-1-piperazinyl)ethyl)-, hydrochloride (1:?)

4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide hydrochloride is a hydrochloride salt that is obtained by reaction of 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide with one equivalent of hydrogen chloride. Highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo. It has a role as an anxiolytic drug and a serotonergic agonist. It contains a 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide(1+).

CAS Number286369-38-8
PubChem CID131905
IUPAC Name4-fluoro-N-[2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl]benzamide;hydrochloride
Molecular FormulaC24H27ClFN3O2
Molecular Weight443.9
Topological Polar Surface Area44.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count31
Formal Charge0
Complexity547
SMILES
COC1=CC2=C(C=CC=C2N3CCN(CC3)CCNC(=O)C4=CC=C(C=C4)F)C=C1.Cl
InChI
InChI=1S/C24H26FN3O2.ClH/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19;/h2-10,17H,11-16H2,1H3,(H,26,29);1H
InChIKey
HWLZKPKZVOLFGK-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Benzamide, 4-fluoro-N-(2-(4-(7-methoxy-1-naphthalenyl)-1-piperazinyl)ethyl)-, hydrochloride (1:?)
CAS: 286369-38-8
CID: 131905
Formula: C24H27ClFN3O2
MW: 443.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight443.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass443.1775830
Monoisotopic Mass443.1775830
Topological Polar Surface Area44.8 Ų
Heavy Atom Count31
Formal Charge0
Complexity547
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19197301-01S 14506 HCl
GTR19175768-01(S, S, S) -AHPC hydrochloride
GTR19156201-01(S, S, S) -AHPC hydrochloride
GTR19264236-01(S, S, S) -AHPC-Me hydrochloride
GTR19202434-01(S) -Viloxazine Hydrochloride
GTR19201896(S) -Azelastine hydrochloride
GTR19280805-01(S) -Cinacalcet hydrochloride
GTR19213330(S) -Verapamil hydrochloride
GTR19201312-01Alaproclate hydrochloride, (S) -
GTR19200885-01S 32212 hydrochloride

Alternative Products

CatalogName
MBS3616282-01S 14506 hydrochloride
HY-110024-01S-14506 (hydrochloride)
464914-01S 14506
HY-110024AS-14506
T28637-01S 14506 HCl
D3190-91GDeoxynojirimycin Hydrochloride (DNJ Hydrochloride)
300563Ligustrazine Hydrochloride (Chuanxiongzine hydrochloride)
OR1043462-01Hydrochloride
C8905-07O-Cyclopropylmethyl-hydroxylamine, Hydrochloride (Cyclopropylmethoxyamine, Hydrochloride, Cyclopropylmethoxylamine, Hydrochloride)
MBS6076243-01N-Butyldeoxynojirimycin, Hydrochloride (Miglustat, Hydrochloride)

Popular Products