HLA-Aw32 & HLA-A25 (MHC I) Mouse Monoclonal Antibody

HLA-Aw32 & HLA-A25 (MHC I) Mouse Monoclonal Antibody

• CAS Number: 9007-83-4
• Gene Name: [HLA-A]
• NCBI Gene ID: 3106
• Reactivity: Human
• Storage Conditions: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Specificity: This MAb reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T-cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This MAb is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.
• Other Gene Names: [HLA-B; HLA-B; AS; HLAB; Bw-47; Bw-50; SPDA1; B-4901; B-5001; HLA-Cw; HLA-B15; HLA-B39; HLA-B49; HLA-B50; HLA-B55; HLA-B59; HLA-B61; HEL-S-83; HLA-DRB1; HLA-B*45ZJ; HLA-B-3506; HLA-B-3905; HLA-B-5502; HLA-B-5602; HLAB]
• Short Name: [HLA-Aw32 & HLA-A25]
• Other Product Names: [major histocompatibility complex, class I, B; HLA class I histocompatibility antigen, B-7 alpha chain; major histocompatibility complex, class I, B; major histocompatibility complex, class I, B; MHC class I antigen B*7]
• NCBI GI Number: 17986001
• NCBI Accession Number: NP_005505.2
• NCBI GB Accession Number: NM_005514.7
• Uniprot Accession Number: P01889