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SNS-314 mesylate

CAT: 0013-GTR19173681-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173681-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SNS-314 Mesylate is a potent and selective pan-Aurora kinase inhibitor, demonstrating high specificity for Aurora A, B, and C with IC50 values of 9, 31, and 3 nM, respectively. It has shown reduced activity against several off-target kinases, including TrkA/B and Fms. This compound is a valuable chemical probe for investigating Aurora kinase biology in cellular and in vivo cancer models.
CAS Number
1146618-41-8
Product Name Alternative
PC-3, HT29, H-1299, A2780, AuroraKinase, Aurora Kinase, Aurora C, Aurora B, Aurora A, ovarian cancer cell, SNS-314, SNS314 Mesylate, SNS-314 Mesylate, SNS 314 Mesylate
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
>98%
Bioactivity
Aurora kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
CS (O) (=O) =O.Clc1cccc (NC (=O) Nc2ncc (CCNc3ncnc4ccsc34) s2) c1
Molecular Formula
C18H15ClN6OS2·CH3SO3H
Molecular Weight
527.04
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1- (3-Chlorophenyl) -3-[5-[2- (thieno[3,2-d]pyrimidin-4-ylamino) ethyl]-1,3-thiazol-2-yl]urea mesylate

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