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Tecastemizole

CAT: 0013-GTR19173667-08Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173667-08Size:500 mg
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Description
Tecastemizole (R 43512) is a selective H1 receptor antagonist and a primary metabolite of astemizole, exhibiting anti-inflammatory properties. It is utilized in pharmacological research to study histamine pathways and inflammation in both in vitro and in vivo experimental models.
CAS Number
75970-99-9
Product Name Alternative
Tecastemizole, R 43512, R43512, R-43512, T 1348, T1348, T-1348, inhibit, Norastemizole, Inhibitor, HistamineReceptor, Histamine Receptor, H1 receptor, anti-inflammatory, allergy
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
99.66% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.17 mM) ; DMSO:60 mg/mL (184.96 mM)
Smiles
Fc1ccc (Cn2c (NC3CCNCC3) nc3ccccc23) cc1
Molecular Formula
C19H21FN4
Molecular Weight
324.4
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Tecastemizole
CAS Number75970-99-9
PubChem CID123618
IUPAC Name1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine
Molecular FormulaC19H21FN4
Molecular Weight324.4
XLogP3.6
Topological Polar Surface Area41.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count24
Formal Charge0
Complexity393
SMILES
C1CNCCC1NC2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F
InChI
InChI=1S/C19H21FN4/c20-15-7-5-14(6-8-15)13-24-18-4-2-1-3-17(18)23-19(24)22-16-9-11-21-12-10-16/h1-8,16,21H,9-13H2,(H,22,23)
InChIKey
SFOVDSLXFUGAIV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tecastemizole
CAS: 75970-99-9
CID: 123618
Formula: C19H21FN4
MW: 324.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight324.4
XLogP33.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass324.17502485
Monoisotopic Mass324.17502485
Topological Polar Surface Area41.9 Ų
Heavy Atom Count24
Formal Charge0
Complexity393
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA5439-5Tecastemizole
HY-105014R-01Tecastemizole (Standard)

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