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Ixazomib

CAT: 0013-GTR19173634-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173634-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ixazomib (MLN2238) is a second-generation, boron-containing proteasome inhibitor that potently targets the chymotrypsin-like (β5) activity of the 20S proteasome, with additional inhibition of its caspase-like (β1) and trypsin-like (β2) sites. It is widely used in preclinical research, including in vitro cell-based assays and in vivo xenograft models, for studying multiple myeloma and other malignancies.
CAS Number
1072833-77-2
Product Name Alternative
20S proteasome, caspase-like (β1), Autophagy, Inhibitor, inhibit, Ixazomib, MLN 2238, MLN2238, MLN-2238, Proteasome
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
Ethanol:9 mg/mL (24.93 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.54 mM) ; DMSO:55 mg/mL (152.34 mM)
Smiles
CC (C) C[C@H] (NC (=O) CNC (=O) c1cc (Cl) ccc1Cl) B (O) O
Molecular Formula
C14H19BCl2N2O4
Molecular Weight
361.03
Storage Conditions
-20°C
Notes
For research use only.

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B2488-5EZSolution™ Ixazomib
RM-I242657-01Ixazomib-D7
MBS577775MLN2238(Ixazomib)
M10726-01Ixazomib Citrate
S2180-10mgIxazomib (MLN2238)
bs-75559C-01Ixazomib [MLN2238]

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