Ixazomib

• Target :

  Proteasome|||Caspase|||Autophagy

• Related Pathways :

  Proteases/Proteasome|||Apoptosis|||Autophagy|||Ubiquitination

• Purity :

  0.9977

• Bioactivity :

  Ixazomib (MLN2238), a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (?5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (?1) and trypsin-like (?2) proteolytic sites (IC50: 31/3500 nM) .

• Smiles :

  CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B(O)O

• Molecular Formula :

  C14H19BCl2N2O4

• Molecular Weight :

  361.03

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1072833-77-2