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LY2109761

CAT: 0013-GTR19173631-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173631-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY2109761 is a potent and selective dual inhibitor of TGF-β receptor types I and II (TβRI/II), with respective Ki values of 38 nM and 300 nM. It effectively blocks Smad2 phosphorylation and is widely used in vitro and in vivo to study TGF-β signaling in cancer, fibrosis, and immunology research.
CAS Number
700874-71-1
Product Name Alternative
Smad, TβRI, TβRII, Transforming growth factor beta receptors, TGF-β/Smad, TGF-β Receptor, TGFβ, TGF-beta, TGFbeta/Smad, TGFbeta, TGFb, TGF-b/Smad, Autophagy, Inhibitor, inhibit, LY2109761, LY-2109761, LY 2109761
Field of Research
Cell Biology, Stem Cell & Developmental Biology
Purity
97.00% (May vary between batches)
Solubility
Ethanol:Insoluble; H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.26 mM) ; DMSO:6.88 mg/mL (15.58 mM)
Smiles
C (CN1CCOCC1) Oc1ccc2c (ccnc2c1) -c1c2CCCn2nc1-c1ccccn1
Molecular Formula
C26H27N5O2
Molecular Weight
441.52
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
C08795-200mgLY2109761

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