TGF-alpha

• Gene Name:

  [TGFA]

• NCBI Gene ID:

  7039

• Reactivity:

  Human, Cow, Rat, Mouse.

• Storage Conditions:

  Antibody without azide - store at -20 to -80°C. Non-hazardous. No MSDS required.

• Specificity:

  This antibody reacts with the C-terminus of TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with Ab-1 is completely blocked by the peptide used for raising this antibody. TGFalpha (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

• Other Gene Names:

  [TGFA; Tgfa; TFGA; TGF-alpha; ETGF]

• Short Name:

  [TGF-alpha]

• Other Product Names:

  [protransforming growth factor alpha isoform 2 preproprotein; Protransforming growth factor alpha; protransforming growth factor alpha; TGF-alpha; transforming growth factor, alpha; EGF-like TGF; ETGF; TGF type 1]

• NCBI GI Number:

  153791414

• NCBI Accession Number:

  NP_001093161.1

• NCBI GB Accession Number:

  NM_001099691.2

• Uniprot Accession Number:

  P01135