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Fedratinib

CAT: 0013-GTR19173525-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173525-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fedratinib is a potent, selective, and orally bioavailable ATP-competitive inhibitor of JAK2 and JAK2V617F. It induces apoptosis in tumor cells and is used in research for myeloproliferative neoplasms, with studies demonstrating efficacy in both cellular assays and animal models.
CAS Number
936091-26-8
Product Name Alternative
CRET, anti-cancer, anti-proliferation, Apoptosis, orally, JAK2, JAK, JAK2 (V617F), JAK2V617F, Janus kinase, myeloproliferative, Inhibitor, inhibit, FLT3, Fedratinib, phosphorylation, STAT5, SAR 302503, SAR302503, SAR-302503, RET, TG101348, TG-101348, TG 101348
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.31% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:240 mg/mL (457.42 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:9.3 mg/mL (17.73 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cc1cnc (Nc2ccc (OCCN3CCCC3) cc2) nc1Nc1cccc (c1) S (=O) (=O) NC (C) (C) C
Molecular Formula
C27H36N6O3S
Molecular Weight
524.68
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
FD151499-01Fedratinib
CS-O-44789Fedratinib-d8
C08814-5mgFedratinib (TG101348)
CS-O-44790Fedratinib-d4
HY-10409R-01Fedratinib (Standard)
HY-10409SFedratinib-d9
A9916-100Fedratinib hydrochloride hydrate
AR-F09859-01Fedratinib Impurity 3
AR-F09858-01Fedratinib Impurity 2

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