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GSK-923295

CAT: 0013-GTR19173383-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173383-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK923295 is a potent and selective allosteric inhibitor of the mitotic kinesin CENP-E, with a reported inhibition constant (Ki) of 3.2 nM. It is a valuable chemical probe for studying mitosis, aneuploidy, and has been utilized in both in vitro biochemical assays and in vivo tumor xenograft models to investigate antimitotic therapies.
CAS Number
1088965-37-0
Product Name Alternative
CENP-E, Apoptosis, Inhibitor, GSK 923295, GSK923295, GSK-923295, Kinesin, inhibit
Field of Research
Cell Biology, Signal Transduction
Purity
96.22% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (4.22 mM) ; DMSO:93 mg/mL (157.06 mM) ; Ethanol:93 mg/mL (157.06 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CC (C) Oc1ccc (cc1Cl) C (=O) N[C@H] (CNC (=O) CN (C) C) Cc1ccc (cc1) -c1cn2cccc ([C@H] (C) O) c2n1
Molecular Formula
C32H38ClN5O4
Molecular Weight
592.13
Storage Conditions
-20°C
Notes
For research use only.

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A3450-10GSK-923295
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A11435-5GSK-923295 5mg
A11435-25GSK-923295 25mg
A11435-50GSK-923295 50mg
A11435-10GSK-923295 10mg
A11435-2GSK-923295 2mg
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A11435-100GSK-923295 100mg
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