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SB225002

CAT: 0013-GTR19173295-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173295-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SB225002 is a selective small molecule antagonist of the CXCR2 chemokine receptor, effectively blocking IL-8 binding. It is widely used in research to investigate CXCR2's role in neutrophil migration, inflammation, and cancer biology in both cellular and animal models.
CAS Number
182498-32-4
Product Name Alternative
Inhibit, Inhibitor, CXCR2, CXCR, CXC chemokine receptors, SB 225002, SB225002, SB-225002
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
96.86% (May vary between batches)
Solubility
DMSO:71.4 mg/mL (202.76 mM) ; Ethanol:3 mg/mL (8.52 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.68 mM)
Smiles
N (C (NC1=C (Br) C=CC=C1) =O) C2=C (O) C=C (N (=O) =O) C=C2
Molecular Formula
C13H10BrN3O4
Molecular Weight
352.14
References & Citations
Yan-Hua Zhao, Juan Chen, Tao Gong, Hai-Yan Ge, Min Li Icariin inhibits tumor-associated neutrophil recruitment via the CXCL8-CXCR2 axis and restrains pro-metastatic programs in colorectal cancer WJG, 32 (11), 113325 (2026)
Storage Conditions
-20°C
Notes
For research use only.

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GTR19196846-01SB220025

Alternative Products

CatalogName
C12846-50mgSB225002
A14209-500SB225002 500mg
A14209-100SB225002 100mg
A14209-25SB225002 25mg
A14209-200SB225002 200mg
A14209-50SB225002 50mg
A14209-10SB225002 10mg
A14209-5SB225002 5mg
A14209-10mM-DSB225002 10mM * 1mL in DMSO

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